Container: Plain (red top)
Collection protocol: Standard venepuncture
Special handling/shipping requirements: Standard
General information about the disease: N/A
General information about when this test is indicated:
Inhibin has been used to help confirm suspected ovarian granulosa cell tumours in the mare. These tumours are hormonally active and can produce inhibin, testosterone and progesterone. A non-pregnant mare with inhibin concentrations greater than 0.7 ng/mL, testosterone concentrations greater than 500-100 pg/mL and progesterone concentrations less than 1 ng/mL is very likely to have a GCT. Note that this assay has not been validated in the horse, and evaluation of this inhibin assay for diagnosis of GCT has not been performed.
Comparison with other related tests:
Testosterone assay is no longer recommended for diagnosis of mare GCT, as the assay cannot detect these relatively low levels of circulating testosterone. Recently, serum Anti-Muellerian hormone (AMH) has been investigated for diagnosis of GCT, but this test has not been evaluated for that purpose at Gribbles Veterinary.