· Post mortem service – just a reminder that our Christchurch laboratory is no longer able to offer a post mortem service. Bodies for PM must be sent directly to our Dunedin or Palmerston North laboratories instead.
· Monitoring Trilostane therapy without using an ACTH stimulation test – In April 2018 a monitoring method was introduced by Dechra in conjunction with Dr Ian Ramsay, University of Glasgow which involves a single cortisol measured on a sample taken pre-Vetoryl tablet. To be able to use this method there are strict criteria which must be met with regards the health of the dogs and their demeanour – i.e. calm, not stressed, well in themselves etc. The information on when to use this test and its interpretation is available on the Dechra website.
Here are the interpretation guidelines we’re using.
Clinical signs and history are very important in interpretation of pre-Vetoryl cortisol monitoring. The presence of PUPD, alopecia, lethargy, distended abdomen, panting, etc. may suggest inadequate control whereas GI signs, PUPD, and weakness may suggest the need for a decreased dose. This monitoring technique is not recommended for dogs that appear highly stressed/aggressive in clinic. In dogs that are clinically unwell (vomiting, diarrhoea, etc.), Vetoryl should be stopped and an ACTH stim performed.
Pre-Vetoryl Cortisol (nmol/L) in dogs with no clinical signs:
<40 Re-evaluate clinical signs, consider lower dose, recheck in 1 month
40-140 Keep current dose, recheck in 3 months
>140 Re-evaluate clinical signs, consider splitting the dose between am/pm or small dose increase, recheck in 1 month
Pre-Vetoryl Cortisol (nmol/L) in dogs with persistent clinical signs of HAC:
<40 Re-evaluate diagnosis of HAC
40 – >140 Consider splitting the dose between am/pm or small dose increase, recheck in 1 monthFurther information including an owner questionnaire can be found at www. dechra.co.uk
· Trace element cheat sheet – trying to decide what TE testing suits your requirements? Check out our cheat sheet here. Perfect to have on hand when on-farm.